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News

Royal Society Wolfson Research Merit Award

News

January, 2019

29th January, 2019

Congratulations to

Hanyu Qin who passed his oral PhD defence!

His work establishes a powerful in vivo lineage tracing system that will open avenues for comprehensive and precise lineage tracing during development, regeneration and disease.

21st January, 2019

Maaike and Manuel published their research in eLIFE

Our manuscript "Primed Track, high-fidelity lineage tracing in mouse pre-implantation embryos using primed conversion of photoconvertible proteins" has been published in eLIFE.

 

Here, we introduce primed Track, a powerful image analysis tool for light-sheet microscopy, that allows for computational correction of drifting specimen to enable accurate lineage tracing of mammalian pre-implantation development even for larger imaging time intervals.

November, 2018

21st November, 2018

Departmental Seminar with

Dr Periklis Pantazis,

Dept. of Bioengineering,

Imperial College London

In recent years, advances in imaging probes, microscopy techniques and bioinformatics image analysis have markedly expanded the imaging toolbox available to developmental biologists. Apart from conventional phenotypic studies, embryonic development is increasingly investigated in vivo with improved accuracy in time and space and more detailed quantitative analyses down to the single-cell level (reviewed in 1). To get more insight into the elaborate chemical and mechanical dynamics that underlie development, my laboratory addresses the growing imaging needs of the biological community by developing assays2, imaging technologies34, and reagents56 for carrying out imaging with i) high spatiotemporal resolution at the single-cell level and with ii) sensitivities down to individual proteins. Such newly introduced and future imaging tools can then be used as a means of performing qualitative and quantitative imaging in order to mechanistically dissect development, disease pro-gression, and tissue regeneration in vivo.

July, 2018

Royal Society Wolfson Research Merit Award

Dr Periklis Pantazis has been awarded the Royal Society Wolfson Research Merit Award, that is administered by the Royal Society, to pursue primed conversion research at Imperial College London.